WebCisplatin has dramatically improved the survival rate of cancer patients, but it has also … WebThirty-eight patients (33%) experienced grade 3 or 4 cisplatin related toxicities with 15 patients (12%) requiring significant dose modification. The reduced dose intensity in Study 99.06 improved tolerability. Incidence of significant late morbidity was low (6%).
Cisplatin treatment of primary and metastatic epithelial
WebNov 20, 2016 · Whole-exome sequencing or targeted exon-capture-based sequencing was performed on 180 tumors. Patients were categorized as cisplatin sensitive or cisplatin resistant by using a combination of postchemotherapy parameters, including serum tumor marker levels, radiology, and pathology at surgical resection of residual disease. WebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu … scania clothes
Sodium Thiosulfate for Protection from Cisplatin-Induced
WebGemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma Invest New Drugs. 2004 Nov;22 (4):475-80. doi: 10.1023/B:DRUG.0000036690.14585.a3. Authors Devansu Tewari 1 , Bradley J Monk , Mark Hunter , Camille A Falkner , Robert A Burger Affiliation WebAbstract Objectives: To determine the efficacy and toxicity of radiation therapy and concurrent weekly cisplatin chemotherapy in achieving a complete clinical and pathologic response when used for the primary treatment of locally-advanced vulvar carcinoma. WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class … scania clothing online