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Cisplatin pubmed

WebCisplatin has dramatically improved the survival rate of cancer patients, but it has also … WebThirty-eight patients (33%) experienced grade 3 or 4 cisplatin related toxicities with 15 patients (12%) requiring significant dose modification. The reduced dose intensity in Study 99.06 improved tolerability. Incidence of significant late morbidity was low (6%).

Cisplatin treatment of primary and metastatic epithelial

WebNov 20, 2016 · Whole-exome sequencing or targeted exon-capture-based sequencing was performed on 180 tumors. Patients were categorized as cisplatin sensitive or cisplatin resistant by using a combination of postchemotherapy parameters, including serum tumor marker levels, radiology, and pathology at surgical resection of residual disease. WebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu … scania clothes https://yahangover.com

Sodium Thiosulfate for Protection from Cisplatin-Induced

WebGemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma Invest New Drugs. 2004 Nov;22 (4):475-80. doi: 10.1023/B:DRUG.0000036690.14585.a3. Authors Devansu Tewari 1 , Bradley J Monk , Mark Hunter , Camille A Falkner , Robert A Burger Affiliation WebAbstract Objectives: To determine the efficacy and toxicity of radiation therapy and concurrent weekly cisplatin chemotherapy in achieving a complete clinical and pathologic response when used for the primary treatment of locally-advanced vulvar carcinoma. WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class … scania clothing online

Ferroptosis: A Novel Anti-tumor Action for Cisplatin - PubMed

Category:Genetic Determinants of Cisplatin Resistance in Patients With ... - PubMed

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Cisplatin pubmed

Oral vinorelbine and cisplatin with concurrent radiotherapy after ...

WebIntroduction: Cisplatin, a platinum-based antineoplastic agent, is the cornerstone for the … WebJan 28, 2024 · In this study, we sought to provide a comprehensive review of the current state of the science highlighting the use of cisplatin in cancer therapy, with a special emphasis on its molecular mechanisms of action, and treatment modalities including the combination therapy with natural products.

Cisplatin pubmed

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WebFeb 5, 2024 · Cisplatin and Oxaliplatin: Our Current Understanding of Their Actions. … WebThe TPF triplet regimen (docetaxel, cisplatin, and 5‐FU) has a trend of further improving treatment efficacy compared with the traditional doublet regimen. 35 , 36 In a phase II study, concurrent chemoradiotherapy with TPF achieved a clinical CR rate of 52.4%, much higher than the previously reported CR rate of 20%. 9 However, the high ...

WebCisplatin induces apoptosis of A549 cells by downregulating peroxidase V Cisplatin treatment induces the ROS production, increases the apoptotic rate and downregulates the Prx expression in A549 cells. Cisplatin treatment induces the ROS production, increases the apoptotic rate and downregulates the Prx expression in A549 cells. WebJun 21, 2024 · This trial compared cisplatin with cisplatin plus delayed administration of …

WebThe cardiotoxic effect of chemotherapeutic agents as cisplatin has become a major issue recently. Interference with mitochondrial dynamics, biogenesis, redox status, and apoptosis are the most possible underlying mechanisms. Semaglutide is a human glucagon-like peptide-1 receptor agonist (GLP-1R), w … WebAug 8, 2010 · Cisplatin is one of the most effective anticancer agents widely used in the …

WebCisplatin is a highly effective antitumor drug generally used in the treatment of solid …

WebWe aimed to evaluate cisplatin pharmacokinetics (PK) and the exposure to unbound … ruby framptonWebCisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer, etc. ruby franke obituaryWebCisplatin is one of the most widely used antineoplastic agents in the treatment of solid tumour and haematological malignancies, including cancers of the testes, ovary, bladder, head and neck, oesophagus, stomach and lung, as well as lymphoma and osteosarcoma. scania clutch servoWebAll studies in which mannitol was used for forced diuresis with cisplatin therapy were evaluated. Data synthesis: Cisplatin therapy can lead to transient and permanent renal impairment. Molecular and histologic changes occur … ruby francis ruschWebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in … scania coffee makerWebOct 7, 2024 · Cisplatin is one of the most widely used chemotherapeutic drugs in the … ruby fractureWebMar 2, 2024 · Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer … scania coach bus